New stool test based on protein stool markers discovered by proteomics
- Post by: OPL
- August 2, 2021
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After the first Annals of Internal Medicine paper describing the proteomics discovery and validation of stool protein for colorectal cancer screening, we now are proud to report the follow-up large scale validation in FIT samples using antibodies. again published in Annals of Internal Medicine.
Bosch LJW, de Wit M, Pham TV, Coupé VMH, Hiemstra AC, Piersma SR, Oudgenoeg G, Scheffer GL, Mongera S, Sive Droste JT, Oort FA, van Turenhout ST, Larbi IB, Louwagie J, van Criekinge W, van der Hulst RWM, Mulder CJJ, Carvalho B, Fijneman RJA, Jimenez CR, Meijer GA. Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study. Ann Intern Med. 2017 Dec 19;167(12):855-866.
de Klaver W, Wisse PHA, van Wifferen F, Bosch LJW, Jimenez CR, van der Hulst RWM, Fijneman RJA, Kuipers EJ, Greuter MJE, Carvalho B, Spaander MCW, Dekker E, Coupé VMH, de Wit M, Meijer GA. Clinical Validation of a Multitarget Fecal Immunochemical Test for Colorectal Cancer Screening : A Diagnostic Test Accuracy Study. Ann Intern Med. 2021 Jul 20.
See also the press release:
https://www.avl.nl/nieuwsberichten/2021/nieuwe-ontlastingstest-kan-darmkankerscreening-verder-verbeteren/