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Phosphoproteomics on leftover material after RNA isolation

  • June 4, 2021
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You throw away leftovers after RNA isolation? Save them and consider performing proteomics. The team of Connie Jimenez could show that RNA-Bee derived protein fractions are very suitable for phosphorylation analysis. In daily practice, different types of biomolecules are usually extracted for large-scale “omics” analysis with tailored protocols. However, when sample material is limited, an […]

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OPL runs biomedical proteomics for PhD students of the EU Marie Curie ITN SECRET (https://secret-itn.eu/) with theory part open to all other (PhD) students and post-docs

  • March 5, 2021
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Week 1 of the course will be on-line and provide participants with a global insight into the field of proteomics, its theory and applications in biomedical research. One day will be dedicated to bioinformatics tools for (prot)eomics data analysis Week 2 will provide participants with hands-on experience with a proteomics experiment and data analysis. Click […]

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Connie elected as Vice-President of the European Proteomics Association

  • December 24, 2020
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The European Proteomics Association (EuPA) (www.eupa.org) is a federation of European 21 national proteomics societies. EuPA aims to strengthen and promote fundamental research and applications, as well as education and training in all areas of proteomics throughout Europe. Connie looks forward to help shape ambitious plans for the coming 3 years that will be carried […]

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Next generation proteomics of international collaborative network published in Nature Communications

  • October 29, 2020
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Sander Piersma and Connie Jimenez of the OncoProteomics Laboratory participated in international benchmark study. Using harmonized mass spectrometry (MS) instrument platforms and standardized data acquisition procedures, we demonstrate robust, sensitive, and reproducible data generation across eleven international sites on seven consecutive days in a 24/7 operation mode.   This work paves the way for large clinical proteomics across multiple sites […]

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INKA analysis in the news

  • October 26, 2020
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Two collaborative papers with the Griffioen and Nowak-Sliwinska labs published that combine functional testing with phosphoproteomics and INKA analysis for selecting optimized drug combinations highlight on swiss television !   Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment. Zoetemelk M, Ramzy GM, Rausch M, Koessler T, van Beijnum JR, Weiss A, […]

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Dutch-Chinese collaborative study published!

  • August 18, 2020
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We report a comprehensive DIA pan-human library consisting of 1096 data-dependent acquisition MS raw files for 16 types of cancer samples. Genomics Proteomics Bioinformatics 2020 Aug 12;S1672-0229(20)30093-0. doi: 10.1016/j.gpb.2019.11.008. DPHL: A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discovery Tiansheng Zhu 1, Yi Zhu 2, Yue Xuan 3, Huanhuan Gao 4, Xue Cai […]

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