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Clinical Proteomics: A Promise Becoming Reality, special MCP issue

  • May 19, 2024
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For everyone interested to know what proteomics can do in their research, a special issue on Clinical Proteomics just came out, guest edited by Steve Carr and Mike Gillette of the MIT Broad Institute and Connie Jimenez: https://www.mcponline.org/special-issue-clinical-proteomics The issue serves to emphasize the field’s growing potential to reshape our understanding of disease and revolutionize […]

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Top Downloaded Article

  • March 28, 2024
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Our review on kinase activity analysis has received enough downloads to rank within the top 10% of papers published in the journal of Mass Spectronomy See Connie’s post.

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OncoProteomics in the spotlight!

  • February 27, 2024
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Last Friday Feb 16 it was our turn to present our work in the Cancer Center Amsterdam seminar series. We discussed our progress in: 1. Phosphoproteomics for individualized precision medicine; 2. Urinary vesicle proteomics for non-invasive prostate cancer diagnosis /prognosis; 3. Identification of protein biomarkers for cisplatin response prediction of response in non-small cell lung […]

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Podcast with Connie Jimenez on high dose vitamin C as promising anti-cancer treatment

  • December 18, 2023
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Our review entitled ” High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer” (Bottger et al.,  J Exp Clin Cancer Res. 2021 Oct 30;40(1):343) is getting attention. Not only in PubMed but now also via a Podcast in the series Decoding Health Care Research.   Watch on youtube: https://youtu.be/eDUWWOkY4S0?si=8O8Ffxrw8PEdnXW6  

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Jan 23, 2024 14.00- 17.30 Proteomics Road Show Amsterdam UMC

  • December 18, 2023
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Celebration of next generation mass spectrometry in the Proteomics Core Facility  Venue:            Auditorium O2 building Date:               14.00- 17.30, 23 Jan. 2023   Program 14.00- 14.15    Inloop (koffie / thee)   14.15-14.20     Welcome (Connie Jimenez, director Proteomics Core Resource) 14.20-14.30     (Phospho)proteomics highlights of the past decade (Connie)   Collaborator orals 14.30-14.45     Proteomics to study […]

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Proteomics identifies biomarkers for chemotherapy response prediction in lung cancer

  • December 18, 2023
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Core question: Can we identify predictive protein biomarkers for the selection of patients benefiting from  platinum-based adjuvant chemotherapy (ACT) in non-small cell lung cancer (NSCLC)? Core insight: Our study published Nov 27th in Molecular Oncology presents the discovery of predictive biomarkers that can aid in distinguishing patients with NSCLC likely to derive clinical benefit from […]

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Personalized treatments – Phosphoproteomics research reveals new avenues for developing targeted therapies for patients with pancreatic cancer

  • October 3, 2023
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In our recent study pubished in Cell Reports, PhD student Andrea Valles shows how profile-guided phosphoproteomics can be used to select low dose combination treatment based on three kinase inhibitors. Kinase activity ranking of individual cell lines using our INKA pipeline, provided the rationale for a combination of within pathway and parallel pathway targeting with triple  […]

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Connie Jimenez highlighted in HUPOST as Human of HUPO

  • September 11, 2023
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Connie Jimenez, The Netherlands   What is your current position and location? I am full Professor of Translational OncoProteomics, Principle Investigator of the OncoProteomics Laboratory and Director of the Proteomics Core Resource, all at Amsterdam University Medical Center, in the beautiful city Amsterdam where I was born, in The Netherlands. How did you get started […]

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