News

New stool test based on protein stool markers discovered by proteomics

  • August 2, 2021
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After the first Annals of Internal Medicine paper describing the proteomics discovery and validation of stool protein for colorectal cancer screening, we now are proud to report the follow-up large scale validation in FIT samples using antibodies. again published in Annals of Internal Medicine. Bosch LJW, de Wit M, Pham TV, Coupé VMH, Hiemstra AC, […]

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Phosphoproteomics on leftover material after RNA isolation

  • June 4, 2021
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You throw away leftovers after RNA isolation? Save them and consider performing proteomics. The team of Connie Jimenez could show that RNA-Bee derived protein fractions are very suitable for phosphorylation analysis. In daily practice, different types of biomolecules are usually extracted for large-scale “omics” analysis with tailored protocols. However, when sample material is limited, an […]

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OPL runs biomedical proteomics for PhD students of the EU Marie Curie ITN SECRET (https://secret-itn.eu/) with theory part open to all other (PhD) students and post-docs

  • March 5, 2021
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Week 1 of the course will be on-line and provide participants with a global insight into the field of proteomics, its theory and applications in biomedical research. One day will be dedicated to bioinformatics tools for (prot)eomics data analysis Week 2 will provide participants with hands-on experience with a proteomics experiment and data analysis. Click […]

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Connie elected as Vice-President of the European Proteomics Association

  • December 24, 2020
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The European Proteomics Association (EuPA) (www.eupa.org) is a federation of European 21 national proteomics societies. EuPA aims to strengthen and promote fundamental research and applications, as well as education and training in all areas of proteomics throughout Europe. Connie looks forward to help shape ambitious plans for the coming 3 years that will be carried […]

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Next generation proteomics of international collaborative network published in Nature Communications

  • October 29, 2020
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Sander Piersma and Connie Jimenez of the OncoProteomics Laboratory participated in international benchmark study. Using harmonized mass spectrometry (MS) instrument platforms and standardized data acquisition procedures, we demonstrate robust, sensitive, and reproducible data generation across eleven international sites on seven consecutive days in a 24/7 operation mode.   This work paves the way for large clinical proteomics across multiple sites […]

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INKA analysis in the news

  • October 26, 2020
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Two collaborative papers with the Griffioen and Nowak-Sliwinska labs published that combine functional testing with phosphoproteomics and INKA analysis for selecting optimized drug combinations highlight on swiss television !   Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment. Zoetemelk M, Ramzy GM, Rausch M, Koessler T, van Beijnum JR, Weiss A, […]

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