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After the first Annals of Internal Medicine paper describing the proteomics discovery and validation of stool protein for colorectal cancer screening, we now are proud to report the follow-up large scale validation in FIT samples using antibodies. again published in Annals of Internal Medicine. Bosch LJW, de Wit M, Pham TV, Coupé VMH, Hiemstra AC, […]

Alexia, Elena, and Merih and learned all about proteomics and performed an experiment on their own samples as well as some Dutch highlights.

You throw away leftovers after RNA isolation? Save them and consider performing proteomics. The team of Connie Jimenez could show that RNA-Bee derived protein fractions are very suitable for phosphorylation analysis. In daily practice, different types of biomolecules are usually extracted for large-scale “omics” analysis with tailored protocols. However, when sample material is limited, an […]

Week 1 of the course will be on-line and provide participants with a global insight into the field of proteomics, its theory and applications in biomedical research. One day will be dedicated to bioinformatics tools for (prot)eomics data analysis Week 2 will provide participants with hands-on experience with a proteomics experiment and data analysis. Click […]

The students were highly motivated, happy to be able to do the practial part on-site and all did very well.

The European Proteomics Association (EuPA) (www.eupa.org) is a federation of European 21 national proteomics societies. EuPA aims to strengthen and promote fundamental research and applications, as well as education and training in all areas of proteomics throughout Europe. Connie looks forward to help shape ambitious plans for the coming 3 years that will be carried […]

ASH20 Abstract Achievement Award granted to Valentina Cordo by the American Society of Hematology !

Our recent publication in Cellular Oncology (Giulia Mantini et al) entitled “Co-expression analysis of pancreatic cancer proteome reveals biology and prognostic biomarkers” is featured on the cover of the December issue.

Sander Piersma and Connie Jimenez of the OncoProteomics Laboratory participated in international benchmark study. Using harmonized mass spectrometry (MS) instrument platforms and standardized data acquisition procedures, we demonstrate robust, sensitive, and reproducible data generation across eleven international sites on seven consecutive days in a 24/7 operation mode.   This work paves the way for large clinical proteomics across multiple sites […]

Two collaborative papers with the Griffioen and Nowak-Sliwinska labs published that combine functional testing with phosphoproteomics and INKA analysis for selecting optimized drug combinations highlight on swiss television !   Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment. Zoetemelk M, Ramzy GM, Rausch M, Koessler T, van Beijnum JR, Weiss A, […]