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It was an honor to participate as plenary speaker in the Joint 12th AOHUPO, 8th AOAPO, and 3rd π-HuB Global Summit, held together with the 13th CNHUPO Congress (aohupo2025.com). Great to see the impressive progress of clinical proteomics in China fuelled by π-HuB seed projects. I would like to thank Tiannan Guo (Westlake), Fuchu He, team members […]

Bladeren door duizend eiwitten. Leuk interview met mij in Janus, populair wetenschappelijke tijdschrift van Amsterdam UMC, door wetenschapsjournalist Rob Buiter en mooie fotos van fotograaf Marieke de Lorijn. Het gesprek ging over de ontwikkeling van The Pan-Cancer Proteome Atlas and het belang van clinical proteomics voor diverse kliniscke toepassingen van screening op darmkanker tot aan phosphoproteomics […]

In this project, we will identify biomarkers to aid individualized multi-kinase inhibitor (MKI) therapy selection in patients with metastatic renal and thyroid cancer. Multiple MKIs are standard-of-care in these cancer types. However, no predictive biomarkers are available to guide their selection and prevent toxicity of ineffective treatment. Profiling of cancer cell lines annotated for drug response and patient […]

At the annual conference of the European Proteomics Association (EuPA) in Saint-Malo, Connie Jimenez received the Juan Pablo Albar Proteome Pioneer Award, in a majority vote by the national proteomics societies of Europe. The award is given to individuals with a leading and long-standing commitment to sharing resources for the development of excellent research in the […]

The idea was conceived at the HUPO 2017 meeting where Tiannan Guo and Connie Jimenez decided to join forces to create a large pan-cancer landscape using DIA-MS. With the HTP capabilities and robustness of the innovative DIA approach, the time was right to perform a large-scale study across multiple tumor types instead of profiling single […]

Phosphoproteome profiling for clinical decision-making in molecular tumor boards   Dr. Annika Schneider Technische Universität München     When:  March 19 2025, 15.30- 16.30 Venue: Lecture Hall, RDC-Adore Research Building, Amsterdam UMC Host: Connie Jimenez   Abstract Precision oncology approaches employing genomics-guided targeted therapy selection for individual cancer patients have provided substantial survival benefits in relatively small […]

In the past 2 weeks, we trained another generation of students and junior scientists in mass spectrometry-based proteomics including hands-on sample preparation, mass spectrometry data generation, data analysis and functional data mining in an interactive bioinformatics practice. This was the first year that PhD students of the Oncology Graduate School Amsterdam joined in, many bringing their […]

Na 18 jaar en 8 maanden was het deze week eindelijk zover: de langverwachte verhuizing! Gisteren was mijn laatste dag in het “tijdelijke” gebouw van de Cancer Center Amsterdam. Met CCA start-up grant, bouwde ik het OncoProteomics Lab. De opdracht die ik kreeg was om hoogstaand kankeronderzoek te gaan doen met cutting-edge proteomics, samen met […]

Exciting times for proteomics, especially in China. The π-HuB project (https://www.pi-hub.org.cn/) will receive several billion yuan over the next 10 years. This great support will catalyze proteomics of the intricate biology of the human body in its many potential states, at unprecedented resolution and scale with transformative implications for health and medicine. Importantly, this big-science […]

HUPO2024 joint with EuPA in Dresden was a great meeting, and an honour to present a keynote lecture on the day of my birthday Oct 21 in the Proteomics in Oncology session in the Plenary. The conference was also a great opportunity to reconnect with my proteomics friends and collegues of Spain, Sweden, Germany, and […]