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The idea was conceived at the HUPO 2017 meeting where Tiannan Guo and Connie Jimenez decided to join forces to create a large pan-cancer landscape using DIA-MS. With the HTP capabilities and robustness of the innovative DIA approach, the time was right to perform a large-scale study across multiple tumor types instead of profiling single […]

Phosphoproteome profiling for clinical decision-making in molecular tumor boards   Dr. Annika Schneider Technische Universität München     When:  March 19 2025, 15.30- 16.30 Venue: Lecture Hall, RDC-Adore Research Building, Amsterdam UMC Host: Connie Jimenez   Abstract Precision oncology approaches employing genomics-guided targeted therapy selection for individual cancer patients have provided substantial survival benefits in relatively small […]

In the past 2 weeks, we trained another generation of students and junior scientists in mass spectrometry-based proteomics including hands-on sample preparation, mass spectrometry data generation, data analysis and functional data mining in an interactive bioinformatics practice. This was the first year that PhD students of the Oncology Graduate School Amsterdam joined in, many bringing their […]

Na 18 jaar en 8 maanden was het deze week eindelijk zover: de langverwachte verhuizing! Gisteren was mijn laatste dag in het “tijdelijke” gebouw van de Cancer Center Amsterdam. Met CCA start-up grant, bouwde ik het OncoProteomics Lab. De opdracht die ik kreeg was om hoogstaand kankeronderzoek te gaan doen met cutting-edge proteomics, samen met […]

Exciting times for proteomics, especially in China. The π-HuB project (https://www.pi-hub.org.cn/) will receive several billion yuan over the next 10 years. This great support will catalyze proteomics of the intricate biology of the human body in its many potential states, at unprecedented resolution and scale with transformative implications for health and medicine. Importantly, this big-science […]

HUPO2024 joint with EuPA in Dresden was a great meeting, and an honour to present a keynote lecture on the day of my birthday Oct 21 in the Proteomics in Oncology session in the Plenary. The conference was also a great opportunity to reconnect with my proteomics friends and collegues of Spain, Sweden, Germany, and […]

Our work published in Molecular Oncology Identification of protein biomarkers for prediction of response to platinum‐based treatment regimens in patients with non‐small cell lung cancer has received over 500 views !

https://www.uu.nl/nieuws/proteomics-pioniers-ruedi-aebersold-en-matthias-mann-ontvangen-de-dr-hp-heinekenprijs-voor-de

For everyone interested to know what proteomics can do in their research, a special issue on Clinical Proteomics just came out, guest edited by Steve Carr and Mike Gillette of the MIT Broad Institute and Connie Jimenez: https://www.mcponline.org/special-issue-clinical-proteomics The issue serves to emphasize the field’s growing potential to reshape our understanding of disease and revolutionize […]

Our review on kinase activity analysis has received enough downloads to rank within the top 10% of papers published in the journal of Mass Spectronomy See Connie’s post.