OPL@HUPO2017 in Dublin: 6 orals and 12 posters!

OPL@HUPO2017 in Dublin: 6 orals and 12 posters

a great success in scientific and social terms!

Postdoc position: Genome and proteome data integration to improve cancer patient treatment

Genome biologist / Computational biologist  (32-36 hrs)

pathology / Cancer Center Amsterdam


Genome and proteome data integration to improve cancer patient treatment


Work environment

At the Cancer Center Amsterdam (CCA) of the VU University Medical Center (VUmc) we perform internationally recognized research in genomics & proteomics. CCA houses state of the art genome technologies and IT-facilities for medical research.


Your challenge

We are looking for an enthusiastic, communicative and pro-active bioinformatician / computational biologist. The work involves support of CCA researchers through training, and hands-on analysis of in house and public genomics and proteomics datasets. A focus will be on exploring tools for data mining, -visualization and -integration. One challenge is to adopt and adapt existing bioinformatics implementations to develop an in silico drug prescription strategy.


Your profile

- University (PhD) education in Life Sciences ie biology and/or biomedical informatics;

- Proven computer programming proficiency and experience with integration of genomics and/ or proteomics data;

- Proficient with scripting languages (Python, Perl);

- Proficient with a statistical framework (R);

- Experience in moving and handling large amounts of (scientific) data reliably and efficiently (UNIX);

- Experience with a database framework (Postgress, MySQL);

- Experience with programming language (C#/C++/C or Java);

- Excellent communication skills and fluency in English (written & spoken).


We offer

Salary scale:  10 (2618 tot 4152 euro based on a 36 hour week), depending on qualifications and experience

In addition to a good monthly salary we offer, among others, 8.3% extra allowance at the end of the year and 8% for holidays. For more information on our conditions, please visit www.werkenbijvumc.nl/arbeidsvoorwaarden (with link to English page).


We offer a young and dynamic environment in health care, covering an active research group in genomics and data analysis.

The project will last 2 years. Employment will initially be for a period of one year, after mutual agreement the contract will be extended till the end of the project.


Additional information

The anticipated start date will be July 1, 2017. Your position is at the VU University Medical Center, within the Cancer Center Amsterdam. For more information you can visit https:/www.vumc.nl/afdelingen/cca-site/ or the Tumor Genome Analysis Core website via http://www.tgac.nl.



For more information about this position, you can contact Prof dr Bauke Ylstra, Dept Pathology, via telephone number: +31(0)20-4442495.
For more information about the application procedure, you can contact Faisca Stuiver, recruiter, via telephone number: +31(0)20-4445635.


Please apply before April 25, 2017 with reference number D5.2017.00068FS via the following link: https://www.werkenbijvumc.nl/vacatures/genome-biologist-computational-biologist/



KWF grant on PDAC phosphoproteomics awarded

Interrogating the phosphoproteome for targets and markers in pancreatic cancer

Pancreatic cancer (PDAC) is a highly lethal and chemoresistant disease. The failure of (targeted) therapies can be attributed to the strong inter- and intra-tumor heterogeneity in terms of complexity of genetic aberrations and the resulting signaling pathway activities, as well as to resistance mechanisms that quickly adapt the tumor to drugs. 

Together this complexity calls for a global post-genomic read-out of aberrant biochemical signaling in clinically relevant models to improve treatment response and outcome of patients with PDAC. We aim to employ phosphoproteomics to understand aberrant signaling and mechanisms underlying drug resistance in PDAC, and we will explore new drug targets and treatment strategies.