The s-test
The s-test supports adapting to different data generating
processes such as modifications of an existing workflow or employing a new method of normalization.
MATLAB code [1] | Dataset 1 NCI-60 [2] | Dataset 2 Phosphoproteomics [3]
[1] T.V. Pham and C.R. Jimenez. Simulated linear test applied to quantitative proteomics. ECCB 2016.
[2] A.M. Gholami, H. Hahne, Z. Wu, F.J. Auer, C. Meng, M. Wilhelm, and B. Kuster (2013). Global proteome analysis of the NCI-60 cell line panel. Cell Reports,
4(3), 609-620.
[3] J.C. van der Mijn, H.J. Broxterman, J.C. Knol, S.R. Piersma, R.R. De Haas,
H. Dekker, T.V. Pham, V.W. van Beusechem, B. Halmos, J.W. Mier, C.R. Jimenez,
, and H.M. Verheul (2016). Sunitinib activates Axl signaling in renal cell
cancer. International Journal of Cancer.
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2016 – Thang Pham