News

Our review on high-dose vitamin C as multi-targeting anti-cancer agent: highly down-loaded in 2021

  • March 26, 2022
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The Journal of Experimental & Clinical Cancer Research (JECCR) has congratulated Connie Jimenez on authoring one of the most-downloaded papers published in the journal during 2021 (‘High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer’). Since publishing, the article has been downloaded 3144 times. Go see the article

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Phosphoproteomics identifies new therapies for T-cell acute lymphoblastic leukemia

  • March 14, 2022
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Our study published Feb. 25 in Nature Communications shows that phosphoproteomic profiling can discover novel targets for therapy for T-ALL and it can guide the design of treatment combination strategies when a single therapy is not sufficient. The analysis of active proteins gives us a more complete picture of the leukemia and allows for selection […]

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PhD defence by David Cucchi

  • October 19, 2021
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16 November 2021 15:45 Fine-tuning prediction of response and survival in acute myeloid leukemia PhD defence by D.G.J. Cucchi

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OPL progress report 2018-2021 on-line

  • September 29, 2021
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This progress report 2018-2021 covers proteomics research of the OncoProteomics Laboratory (OPL) and collaborators, as well as proteomics activities performed in the context of our function as Proteomics Core Facility. It harbors information on our mass spectrometry infrastructure and proteomics expertise, output, academic activities and includes summaries of running core and collaborative projects.

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New stool test based on protein stool markers discovered by proteomics

  • August 2, 2021
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After the first Annals of Internal Medicine paper describing the proteomics discovery and validation of stool protein for colorectal cancer screening, we now are proud to report the follow-up large scale validation in FIT samples using antibodies. again published in Annals of Internal Medicine. Bosch LJW, de Wit M, Pham TV, Coupé VMH, Hiemstra AC, […]

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Phosphoproteomics on leftover material after RNA isolation

  • June 4, 2021
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You throw away leftovers after RNA isolation? Save them and consider performing proteomics. The team of Connie Jimenez could show that RNA-Bee derived protein fractions are very suitable for phosphorylation analysis. In daily practice, different types of biomolecules are usually extracted for large-scale “omics” analysis with tailored protocols. However, when sample material is limited, an […]

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OPL runs biomedical proteomics for PhD students of the EU Marie Curie ITN SECRET (https://secret-itn.eu/) with theory part open to all other (PhD) students and post-docs

  • March 5, 2021
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Week 1 of the course will be on-line and provide participants with a global insight into the field of proteomics, its theory and applications in biomedical research. One day will be dedicated to bioinformatics tools for (prot)eomics data analysis Week 2 will provide participants with hands-on experience with a proteomics experiment and data analysis. Click […]

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